Posts Tagged ‘Osteoclasts’
Powerful Osteoporosis Drug
Osteoporosis is a chronic and widespread disease that disrupts the formation of minerals to the bones become brittle, resulting in great pain and increased fractures. This problem increases significantly as the population ages. Arthritis, which involves inflammation of the joints, is another example. Thanks to advances in nanomedicine may develop potential cure or treatment (some already mentioned in a previous post). A therapy capable of increasing the quantity and activity of osteoblasts, bone forming cells, has opened a new door in the treatment of osteoporosis due to its physiological mechanism of action endorsed by several clinical trials.
Spain Osteoporosis affects one in four women over 65. The bone loss that characterizes this disease ends up causing fractures of low-energy trauma, resulting in pain and loss in quality of life. Osteoporotic bone regeneration is a coherent and physiological therapeutic strategy so far has not been used in any of the treatments available, with mechanisms of action focusing exclusively on curbing the bone degeneration.
Now, thanks to biotechnology and recombinant DNA techniques, has designed a molecule capable of stimulating bone-forming cells, osteoblasts, so that is done to restore lost bone mass. So far the available drugs inhibit the activity of bone-destroying cells, osteoclasts, the new molecule, teriparatide, inhibits not only destructive, it increases the activity and amount of the creators of bone. Read the rest of this entry »